Darryle Schoepp: search on Z-Library

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1

SAR study of a subtype selective allosteric potentiator of metabotropic glutamate 2 receptor, N-(4-phenoxyphenyl)-N-(3-pyridinylmethyl)ethanesulfonamide

David A. Barda, Zhao-Qing Wang, Thomas C. Britton, Steven S. Henry, G.Erik Jagdmann, Darrell S. Coleman, Michael P. Johnson, Sherri L. Andis, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 264 KB

english, 2004

2

Metabotropic glutamate receptors as novel targets for anxiety and stress disorders

Swanson, Chad J., Bures, Mark, Johnson, Michael P., Linden, Anni-Maija, Monn, James A., Schoepp, Darryle D.

Journal:

Nature Reviews Drug Discovery

Year:

2005

Language:

english

File:

PDF, 396 KB

english, 2005

3

LY354740, an mGlu2/3 Receptor Agonist as a Novel Approach to Treat Anxiety/Stress

Schoepp, Darryle D., Wright, Rebecca A., Levine, Louise R., Gaydos, Brenda, Potter, William Z.

Journal:

Year:

2003

Language:

english

File:

PDF, 336 KB

english, 2003

4

Metabotropic glutamate receptors, 5 years on

Collingridge, Graham L., Manahan-Vaughan, Denise, Nicoletti, Ferdinando, Schoepp, Darryle D.

Journal:

Neuropharmacology

Year:

2017

Language:

english

File:

PDF, 1002 KB

english, 2017

5

SAR Study of a Subtype Selective Allosteric Potentiator of Metabotropic Glutamate 2 Receptor, N-(4-Phenoxyphenyl)-N-(3-pyridinylmethyl)ethanesulfonamide.

David A. Barda, Zhao-Qing Wang, Thomas C. Britton, Steven S. Henry, G. Erik Jagdmann, Darrell S. Coleman, Michael P. Johnson, Sherri L. Andis, Darryle D. Schoepp

Journal:

Year:

2004

File:

PDF, 22 KB

2004

6

Synthesis, Structure Elucidation, and Pharmacological Evaluation of 5-Methyl-oxymorphone (= 4,5α-epoxy-3,14-dihydroxy-5,17-dimethylmorphinan-6-one)

Helmut Schmidhammer, Jack B. Deeter, Noel D. Jones, J. David Leander, Darryle D. Schoepp, John K. Swartzendruber

Journal:

Helvetica Chimica Acta

Year:

1988

Language:

english

File:

PDF, 243 KB

english, 1988

7

Synthesis of a mGluR5 antagonist using [11C]copper(I) cyanide

William B. Mathews, James A. Monn, Hayden T. Ravert, Daniel P. Holt, Darryle D. Schoepp, Robert F. Dannals

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2006

Language:

english

File:

PDF, 148 KB

english, 2006

8

Second-messenger responses in brain slices to elucidate novel glutamate receptors

Darryle D. Schoepp, Bryan G. Johnson, Craig R. Salhoff, Rebecca A. Wright, John S. Goldsworthy, S. Richard Baker

Journal:

Journal of Neuroscience Methods

Year:

1995

Language:

english

File:

PDF, 798 KB

english, 1995

9

(2S,1′S,2′R,3′R)-2(2′-Carboxy-3′-hydroxymethylcyclopropyl)glycine-[3H], a potent and selective radioligand for labeling group 2 and 3 metabotropic glutamate receptors

William J. Wheeler, Dean K. Clodfelter, Palaniappan Kulanthaivel, Concepcion Pedregal, Eli A. Stoddard, Rebecca A. Wright, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 282 KB

english, 2005

10

Enzymatic resolution and pharmacological activity of the enantiomers of 3,5-dihydroxyphenylglycine, a metabotropic glutamate receptor agonist

S. Richard Baker, John Goldsworthy, Raymond C. Harden, Craig R. Salhoff, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 289 KB

english, 1995

11

Corrigendum to “(2S,1′S,2′R,3′R)-2(2′-Carboxy-3′-hydroxymethylcyclopropyl)glycine–[3H], a potent and selective radioligand for labeling group 2 and 3 metabotropic glutamate receptors” [Bioorg. Med. Chem. Lett. 15 (2005) 349]

William J. Wheeler, Dean K. Clodfelter, Ivan Collado, Palaniappan Kulanthaivel, Concepcion Pedregal, Eli A. Stoddard, Rebecca A. Wright, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 54 KB

english, 2005

12

Synthesis and pharmacological characterization of l-trans-4-tetrazolylproline (ly300020): A novel systemically-active ampa receptor agonist

James A. Monn, Matthew J. Valli, Rebecca A. True, Darryl D. Schoepp, J.David Leander, David Lodge

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 341 KB

english, 1993

13

Tetrazole amino acids as competitive NMDA antagonists

Paul L. Ornstein, M.Brian Arnold, Debbie Evrard, J.David Leander, David Lodge, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 391 KB

english, 1993

14

Muscarinic antagonist activity of 3-(5-alkoxy-oxazol-2-yl)-1,2,5,6-tetrahydropyridines.

Charles H. Mitch, Frank P. Bymaster, David O. Calligaro, Steven J. Quimby, Darryle D. Schoepp, David T. Wong, Harlan E. Shannon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 288 KB

english, 1994

15

Unusual stereochemical preferences of decahydroisoquinoline-3-cargoxylic acid competitive NMDA antagonists

Paul L. Ornstein, M.Brian Arnold, Nancy K. Augenstein, Jack B. Deeter, J.David Leander, David Lodge, David O. Calligaro, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 439 KB

english, 1993

16

Structure-activity studies of aryl-spaced decahydroisoquinoline-3-carboxylic acid ampa receptor antagonists

Thomas J. Bleisch, Paul L. Ornstein, Nancy K. Allen, Rebecca A. Wright, David Lodge, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 333 KB

english, 1997

17

Heteroatom-substitution as a strategy for increasing the potency of competitive NMDA antagonists

Paul L. Ornstein, M.Brian Arnold, William H.W. Lunn, Lawrence J. Heinz, J.David Leander, David Lodge, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 315 KB

english, 1998

18

(2S,4S)-2-Amino-4-(2,2-diphenylethyl)pentanedioic acid selective group 2 metabotropic glutamate receptor antagonist

Ana Escribano, Jesus Ezquerra, Concepción Pedregal, Almudena Rubio, Belén Yruretagoyena, S.Richard Baker, Rebecca A. Wright, Bryan G. Johnson, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 288 KB

english, 1998

19

[3H]LY341495, a highly potent, selective and novel radioligand for labeling group II metabotropic glutamate receptors

Paul L. Ornstein, M.Brian Arnold, Thomas J. Bieisch, Rebecca A. Wright, William J. Wheeler, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 183 KB

english, 1998

20

Synthesis and metabotropic glutamate receptor antagonist activity of N1-substituted analogs of 2R,4R-4-aminopyrrolidine-2,4-dicarboxylic acid

Matthew J Valli, Darryle D Schoepp, Rebecca A Wright, Bryan G Johnson, Ann E Kingston, Rosemarie Tomlinson, James A Monn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 323 KB

english, 1998

21

2,3′-disubstituted-2-(2′-carboxycyclopropyl)glycines as potent and selective antagonists of metabotropic glutamate receptors

Iván Collado, Jesús Ezquerra, Angel Mazón, Concepción Pedregal, Belén Yruretagoyena, Anne E. Kingston, Rosemary Tomlinson, Rebecca A. Wright, Bryan G. Johnson, Darryle D. Schoepp

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 342 KB

english, 1998

22

Synthesis and Structure–Activity Relationship Studies of Novel 2-Diarylethyl Substituted (2-Carboxycycloprop-1-yl)glycines as High-Affinity Group II Metabotropic Glutamate Receptor Ligands

Ulrik S Sørensen, Thomas J Bleisch, Anne E Kingston, Rebecca A Wright, Bryan G Johnson, Darryle D Schoepp, Paul L Ornstein

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 250 KB

english, 2003

23

Molecular Cloning, Expression, and Pharmacological Characterization of humEAA1, a Human Kainate Receptor Subunit

Rajender K. Kamboj, Darryle D. Schoepp, Stephen Nutt, Lee Shekter, Bozena Korczak, Rebecca A. True, Vikarna Rampersad, Dennis M. Zimmerman, Michael A. Wosnick

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 1.06 MB

english, 1994

24

Disruption of Potential α-Helix in the G Loop of the Guinea: Pig 5-Hydroxytryptamine2 Receptor Does Not Prevent Receptor Coupling to Phosphoinositide Hydrolysis

Stephanie W. Watts, Marlene L. Cohen, Patrick Q. Mooney, Bryan G. Johnson, Darryle D. Schoepp, Melvyn Baez

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 1.07 MB

english, 1994

25

Cyclothiazide Selectively Potentiates AMPA- and Kainate-Induced [3H]Norepinephrine Release from Rat Hippocampal Slices

Manisha A. Desai, J. Paul Burnett, Darryle D. Schoepp

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 750 KB

english, 1994

26

Distribution and Ontogeny of 1S,3R-1-Aminocyclopentane-1,3-Dicarboxylic Acid-Sensitive and Quisqualate-Insensitive [3H]Glutamate Binding Sites in the Rat Brain

Rebecca A. Wright, John W. McDonald, Darryle D. Schoepp

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 1010 KB

english, 1994

27

3,5-Dihydroxyphenylglycine Is a Highly Selective Agonist for Phosphoinositide-Linked Metabotropic Glutamate Receptors in the Rat Hippocampus

Darryle D. Schoepp, John Goldsworthy, Bryan G. Johnson, Craig R. Salhoff, S. Richard Baker

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 428 KB

english, 1994

28

Excitotoxicity at Both NMDA and Non-NMDA Glutamate Receptors Is Antagonized by Aurintricarboxylic Acid: Evidence for Differing Mechanisms of Action

Gail D. Zeevalk, Darryl Schoepp, William J. Nicklas

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 1.14 MB

english, 1995

29

(1S,3R)-1-Aminocyclopentane-1,3-Dicarboxylic Acid-Induced Increases in Cyclic AMP Formation in the Neonatal Rat Hippocampus Are Mediated by a Synergistic Interaction Between Phosphoinositide- and Inhibitory Cyclic AMP-Coupled mGluRs

Darryle D. Schoepp, Bryan G. Johnson, James A. Monn

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 582 KB

english, 1996

30

Regulation of Neurotransmitter Release by Metabotropic Glutamate Receptors

Jayne Cartmell, Darryle D. Schoepp

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 319 KB

english, 2000

31

The Potent, Selective mGlu2/3 Receptor Agonist LY379268 Increases Extracellular Levels of Dopamine, 3,4-Dihydroxyphenylacetic Acid, Homovanillic Acid, and 5-Hydroxyindole-3-Acetic Acid in the Medial Prefrontal Cortex of the Freely Moving Rat

Jayne Cartmell, Kenneth W. Perry, Craig R. Salhoff, James A. Monn, Darryle D. Schoepp

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 212 KB

english, 2000

32

The mGlu2/3 receptor agonist, LY354740, blocks immobilization-induced increases in noradrenaline and dopamine release in the rat medial prefrontal cortex

Chad J. Swanson, Kenneth W. Perry, Darryle D. Schoepp

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 216 KB

english, 2004

33

Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl)glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes

Rebecca A. Wright, M. Brian Arnold, William J. Wheeler, Paul L. Ornstein, Darryle D. Schoepp

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2000

Language:

english

File:

PDF, 134 KB

english, 2000

34

Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s)

Michael P. Johnson, David Barda, Thomas C. Britton, Renee Emkey, William J. Hornback, G. Erik Jagdmann, David L. McKinzie, Eric S. Nisenbaum, Joseph P. Tizzano, Darryle D. Schoepp

Journal:

Psychopharmacology

Year:

2005

Language:

english

File:

PDF, 393 KB

english, 2005

35

Alteration of Dopamine Synthesis in Rat Striatum Subsequent to Selective Type A Monoamine Oxidase Inhibition

Darryle D. Schoepp, Albert J. Azzaro

Journal:

Journal of Neurochemistry

Year:

1981

Language:

english

File:

PDF, 372 KB

english, 1981

36

Specificity of Endogenous Substrates for Types A and B Monoamine Oxidase in Rat Striatum

Darryle D. Schoepp, Albert J. Azzaro

Journal:

Journal of Neurochemistry

Year:

1981

Language:

english

File:

PDF, 597 KB

english, 1981

37

Effects of Intrastriatal Kainic Acid Injection on [3H]Dopamine Metabolism in Rat Striatal Slices: Evidence for Postsynaptic Glial Cell Metabolism by Both the Type A and B Forms of Monoamine Oxidase

Darryle D. Schoepp, Albert J. Azzaro

Journal:

Journal of Neurochemistry

Year:

1983

Language:

english

File:

PDF, 851 KB

english, 1983

38

Norepinephrine Stimulation of Phosphoinositide Hydrolysis in Rat Cerebral Cortex Is Associated with the Alpha1-Adrenoceptor

Darryle D. Schoepp, Sheila M. Knepper, Charles O. Rutledge

Journal:

Journal of Neurochemistry

Year:

1984

Language:

english

File:

PDF, 418 KB

english, 1984

39

Further Studies on the Nature of Postsynaptic Dopamine Uptake and Metabolism in Rat Striatum: Sodium Dependency and Investigation of a Possible Role for Carrier-Mediated Uptake into Serotonin Neurons

Darryle D. Schoepp, Albert J. Azzaro

Journal:

Journal of Neurochemistry

Year:

1985

Language:

english

File:

PDF, 627 KB

english, 1985

40

Manganese Stimulates the Incorporation of [3H]Inositol into a Pool of Phosphatidylinositol in Brain That Is Not Coupled to Agonist-Induced Hydrolysis

Darryle D. Schoepp

Journal:

Journal of Neurochemistry

Year:

1985

Language:

english

File:

PDF, 636 KB

english, 1985

41

Excitatory Amino Acid Agonist-Antagonist Interactions at 2-Amino-4-Phosphonobutyric Acid-Sensitive Quisqualate Receptors Coupled to Phosphoinositide Hydrolysis in Slices of Rat Hippocampus

Darryle D. Schoepp, Bryan G. Johnson

Journal:

Journal of Neurochemistry

Year:

1988

Language:

english

File:

PDF, 896 KB

english, 1988

42

Comparison of Excitatory Amino Acid-Stimulated Phosphoinositide Hydrolysis and N-[3H]Acetylaspartylglutamate Binding in Rat Brain: Selective Inhibition of Phosphoinositide Hydrolysis by 2-Amino-3-Phosphonopropionate

Darryle D. Schoepp, Bryan G. Johnson

Journal:

Journal of Neurochemistry

Year:

1989

Language:

english

File:

PDF, 573 KB

english, 1989

43

Inhibition of Excitatory Amino Acid-Stimulated Phosphoinositide Hydrolysis in the Neonatal Rat Hippocampus by 2-Amino-3-Phosphonopropionate

Darryle D. Schoepp, Bryan G. Johnson

Journal:

Journal of Neurochemistry

Year:

1989

Language:

english

File:

PDF, 554 KB

english, 1989

44

In Vitro and In Vivo Pharmacology of trans- and cis-(±)-1-Amino-1,3-Cyclopentanedicarboxylic Acid: Dissociation of Metabotropic and Ionotropic Excitatory Amino Acid Receptor Effects

Darryle D. Schoepp, Bryan G. Johnson, Craig R. Salhoff, John W. McDonald, Michael V. Johnston

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 822 KB

english, 1991

45

Metabotropic Glutamate Receptor Activation Produces Extrapyramidal Motor System Activation That Is Mediated by Striatal Dopamine

Aida I. Sacaan, Frank P. Bymaster, Darryle D. Schoepp

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 764 KB

english, 1992

46

Inhibition of Cyclic AMP Formation by a Selective Metabotropic Glutamate Receptor Agonist

Darryle D. Schoepp, Bryan G. Johnson, James A. Monn

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 367 KB

english, 1992

47

Aurintricarboxylic Acid Prevents NMDA-Mediated Excitotoxicity: Evidence for Its Action as an NMDA Receptor Antagonist

Gail D. Zeevalk, Darryle Schoepp, William J. Nicklas

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 501 KB

english, 1993

48

LY3 54740: A Systemically Active mGlu2/mGlu3 Receptor Agonist

Darryle D. Schoepp, James A. Monn, Gerard J. Marek, George A Ghajanian, Bita Moghaddam

Journal:

CNS Drug Reviews

Year:

1999

Language:

english

File:

PDF, 143 KB

english, 1999

49

Group II Selective Metabotropic Glutamate Receptor Agonists and Local Cerebral Glucose Use in the Rat

Lam, Amy G. M., Monn, James A., Schoepp, Darryle D., Lodge, David, McCulloch, James

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

1999

Language:

english

File:

PDF, 1002 KB

english, 1999

50

A Role for Noradrenergic Transmission in the Actions of Phencyclidine and the Antipsychotic and Antistress Effects of mGlu2/3 Receptor Agonists

CHAD J. SWANSON, DARRYLE D. SCHOEPP

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 2.12 MB

2003

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